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Mary E. Delany, Ph.D.
Professor of Developmental Genetics
John and Joan Fiddyment Endowed Chair in Agriculture
Interim Dean, College of Agricultural and Environmental Sciences
Associate Dean, College of Agricultural and Environmental Sciences 2009-12
Chair, Animal Science 2005-09
530-754-9343 (faculty office)
530-754-9404 (laboratory)
530-752-0233 (CA&ES dean’s office)
530-752-0175 (FAX)
E-mail: medelany@ucdavis.edu
Web:
http://animalscience.ucdavis.edu/faculty/delany/ |
Education
B.S., Montclair State College, Montclair NJ, 1979.
M.S., Cornell University, Ithaca NY, 1984.
Ph.D., Cornell University, Ithaca NY, 1987.
Research Interests
My laboratory research focuses on avian telomere biology, with
chicken being the primary organism under study. Our studies concentrate on
the organization, inheritance, regulation and stability of telomere array
organization in normal, immortalized and transformed cell systems, both in
vitro and in vivo. Telomere stability is one of the most significant genetic
mechanisms controlling overall genome stability and influencing cellular
proliferation, senescence and transformation. Current projects include
analysis of the regulation and function of the telomere-telomerase pathway
during oncogenesis induced by Marek’s disease virus (MDV), a DNA herpes
virus which induces T-cell lymphomas and results in a high level of
mortality. This particular disease is a problem of enormous significance for
the poultry industry. MDV infection and disease in chickens also serves as a
model system for human herpes virus infection and disease conditions (e.g.,
Burkitt’s lymphoma caused by Epstein Barr virus). Students studying in the
lab (M.S. and Ph.D.) are trained in the disciplines of genetics,
cytogenetics, and genomics with an emphasis on avian systems as well as
comparative vertebrate biology. Research and technology levels range from
molecular and cellular to the organismal. Other interests and areas of
research include gene mapping and chromosome organization, congenital and
inherited developmental mutations, and conservation of poultry and avian
genetic resources.
Graduate Group Member
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